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Thorne Research 0693749114024

Thorne Research Niasafe-600 180 vcaps

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Inositol hexaniacinate - a safer, non-flushing alternative to niacin

  • provides a higher amount of niacin without the flushing*
  • unlike time-release niacin, Niasafe is easy on the liver*
  • supports peripheral vascular circulation*

Niacin has long been used to support good cardiovascular health.* It has been proven effective at helping to maintain already normal levels of cholesterol.*

The side effects of high amounts of niacin that may occur range from flushing and itching to liver toxicity and impaired glucose tolerance. Therefore, the need for a safer approach to niacin supplementation resulted in the investigation of niacin esters. One of the most widely studied niacin esters is inositol hexaniacinate (IHN). In numerous trials IHN has been found to be virtually free of the side effects associated with conventional niacin therapy.* Pharmacokinetic studies show the IHN molecule is absorbed intact and slowly hydrolyzed in the bloodstream, releasing free niacin and inositol and having a diminished impact on the liver.* Maximum serum levels are reached approximately 10 hours after ingestion, thus allowing for a more delayed release of niacin that reduces the risk of flushing.*

A review of the literature reveals numerous positive studies on the use of IHN to support good circulatory health, particularly the support of vascular circulation to the extremities.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

Serving Size: 1 vcapsule
Servings per Container: 180

Directions for Use: Take 1 capsule one to three times daily or as recommended by a health-care practitioner.

Other Directions: ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

EXCIPIENT FREE
This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates.

PREGNANCY WARNING
If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS/CONTRAINDICATIONS
There are no known adverse interactions or contraindications at publication date.

  •  
    Amount per Serving
    % Daily Value
  •  Niacin (as Inositol Hexaniacinate)
     540mg
     2700%

* Daily value not established
These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.

Other Ingredients
Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.


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