Joint Comfort from Pure Encapsulations

Joint comfort is a key issue for many mature men and women. Pure Encapsulations’ high quality nutritional supplements offer support for healthy joint, connective tissue and cartilage through a number of mechanisms. Functional ingredients for joint mobility and comfort include building blocks to support cartilage composition and herbal extracts to maintain healthy immune mediator activity.*

Boswellia serrata, an Ayurvedic herb, has a long history of use for connective tissue and joint support. Boswellic acids, the active terpenoid constituents of boswellia, target 5-lipoxygenase enzyme activity to maintain healthy leukotriene metabolism. In addition, evidence suggests that boswellic acids target the leukocyte elastase enzyme to maintain connective tissue integrity. The combination of these two actions is believed to be unique to boswellia. As a result of its effect on 5-lipoxygenase, boswellia also plays a key role in supporting colon health. Boswellia extract, standardized to contain 70 percent boswellic acids, promotes healthy joint, connective tissue and colon function primarily by maintaining healthy leukotriene metabolism.*

Disc-Flex is an advanced intervertebral disc support formula combining hydrolyzed collagen complex, glucosamine, vitamins K2 and D, and herbal extracts to promote healthy disc composition, strength, flexibility and comfort. This formula addresses the unique nutritional needs of intervertebral cartilage (IVC). IVC is avascular, wears differently and is affected by different nutritional factors compared to articular cartilage. A healthy disc composition depends on glucosamine, chondroitin and collagen. Studies indicate that glucosamine and chondroitin supplements support spinal disc integrity and have the potential to support the strength of the disc under compressive loads. L-Carnosine, alpha lipoic acid and grape seed extract offer additional support by maintaining healthy advanced glycation end product metabolism and antioxidant defenses. Vitamin K2, in the form of menaquinone-7, maintains a healthy balance of calcium uptake into extra-skeletal tissues. In cooperation with vitamin K2, vitamin D supports healthy cartilage end plate calcium metabolism. Boswellia and devil’s claw target immune mediators and enzymes for day-to-day spinal comfort, flexibility and musculoskeletal comfort.*

Hyaluronic Acid, or HA, is a naturally occurring polymer found in every tissue of the body. It is particularly concentrated in the skin and in synovial fluid, but its levels decline with age. HA serves to attract and retain water in the extracellular matrix of tissues. In  joints, HA is critical for lubrication and shock absorption. Preclinical studies indicate that HA also modulates prostaglandin production, an additional mechanism that maintains tissue health. Many HA preparations are of extremely high molecular weight and too large to be absorbed from the intestine. HyaMax® sodium hyaluronate is a low molecular weight HA produced through a natural fermentation process. In a pharmacokinetic study, orally administered HyaMax® hyaluronic acid was incorporated into joints, connective tissue and skin, with a particular affinity for cartilaginous joints.  Through both structural and functional mechanisms, HyaMax® supports overall joint, skin and tissue health.*

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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