Thorne Research 5-Hydroxytryptophan 90 vcaps
Enhances serotonin production*
- increases serotonin levels for sleep enhancement decreased sugar cravings and better stress management*
- can be taken with meals without competing with other amino acids
- includes vitamin B6 for optimal activity
- made without flowing agents that can inhibit bioavailability
5-Hydroxytryptophan (5-HTP) is the intermediate metabolite produced when the body initiates the process of converting the essential amino acid L-tryptophan to serotonin. Serotonin levels in the body are associated with the regulation of sleep mood aggression appetite temperature sexual behavior and pain sensation.*
Supplementing with 5-HTP to facilitate serotonin production is preferable to supplementing with L-tryptophan because unlike L-tryptophan 5-HTP cannot be shunted into niacin or protein production.* Supplementation with 5-HTP bypasses the conversion of L-tryptophan into 5-HTP by the enzyme tryptophan hydroxylase the rate-limiting step in the synthesis of serotonin and a step that can be inhibited by a number of factors including stress insulin resistance increasing age and deficiencies of vitamin C folate and iron.
5-HTP is well absorbed when taken orally with about 70 percent ending up in the bloodstream.*
Intestinal absorption of 5-HTP does not require the presence of a transport molecule and is not affected by the presence of other amino acids; therefore it may be taken with meals without reducing its effectiveness.* 5-HTP easily crosses the blood-brain barrier and effectively increases central nervous system (CNS) synthesis of serotonin.*
5-HTP has been shown to have a beneficial impact on mood discomfort associated with fatigue sleep and carbohydrate craving.* Numerous studies of individuals with negative mood status have shown significant positive response with 50-300 mg of 5-HTP daily.*
To further facilitate serotonin production Thorne Research's 5-HTP formula contains pyridoxal 5'-phosphate the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin.* 5-HTP is commercially produced by extraction from the seeds of the African plant Griffonia simplicifolia.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose treat cure or prevent any disease.